Objectives
My researches concern particularly the areas of activities :
Physics / Biology / Chemistry
Education / Training
R/D / Science / Scientific Research
My dual training program in both organic chemistry and biochemistry gave me the opportunity to easily comprehend biological problems through a chemist’s eye. It has also given me the chance to better myself and my scientific skills while allowing me to occupy a turn point position in a medicinal chemistry laboratory; on the verge of both exciting sciences.
While actively participating in modern research projects for the past five years, I have also developed a passion for reading, writing and reviewing scientific publications. The daily usage of computers has granted me multiple computer skills. My very rich teaching experience has given me a new point of view in science. As a matter of fact, being able to teach chemistry (both organic and inorganic) is no easy task. It requires dynamism and a very strong communicational aptitude.
I strongly believe that my intensive scientific training and my love of scientific specialties such as organic chemistry, biochemistry and biology, along with my general enthusiasm, perfectionism, organizational and communication skills, will be the keys to my integration in your group.
I am currently looking for a position in research & development in both industry or academia.
Education
University Louis Pasteur - Strasbourg,France
September 2002 - October 2005
PhD in Organic Chemistry and Cell Biology
Organic synthesis of Quinol Fatty Alcohols and evaluation of their biological activity
Area of specialisation :Organic Chemisty - Cell Biology
University Louis Pasteur - Strasbourg, France
September 2000 - June 2002
Master's degree in Biochemistry and Organic Chemistry
1st year : Structural biochemistry
2nd year : Organic chemistry
University Louis Pasteur - Strasbourg, France
September 1997 - June 2000
Bachelor's degree in Biology and Biochemistry
Experience
Research associate
Mission : Organic syntheses of radio-labelled fatty acids
Means : * Organic chemistry
* Purification methods
* Radio-chemistry
Research associate
Mission : Organic syntheses of novel dipyridiny-piridazine ligands.
Means : * Organic synthesis
* organometallic and macromolecular synthesis
Assistant professor
University of Orléans, France
Mission : Research : Organic synthesis of modified nucleosides as new potent antiviral therapies.
Teaching : Organic chemistry at all levels (bachelor's and master's).
Postdoctoral fellow
University of Maryland, College Park, USA
Mission : Organic syntheses of Iodotyrosine Deiodinase inhibitors. This enzyme is essential to the recycling of iodine within the tyroïd. Two different compounds have been synthesized : a difluoromethyl and an oxaspiro derivative of tyrosine.
Means : Organic synthesis
Analytical methods
Doctoral fellow
University Louis Pasteur - Strasbourg, France
Mission : Five series of hybrid compounds bearing a long chain fatty alcohol and a quinol ring (Quinol Fatty Alcohols) were synthesized. C-alkylated QFAs were obtained by a Sonogashira cross-coupling reaction between various arylbromides and terminal alkynes. N- or O-alkylated homologues were obtained by SN2 type reactions.
These different compounds have very good antioxidant activities in their demethylated form sometimes reaching a hundred-fold increase relative to Trolox®, a known antioxidant. On the other hand, the QFAs, and especially QFA15, bearing 15 carbon atoms on the side chain, have the capacity to promote axonal growth. QFA15 allows proper axonal extension at nanomolar concentration, on both normal and inhibitory substrates.
Means : * Organic syntheses
* Solid support synthesis
* Analytical methods
* Bibliographic tools
* Computer skills
* Cell biology & Neuroscience
Appraisal : * 5 scientific publications
* 2 patents
Languages
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English
Speaking competence : Fluent , Written competence : Fluent -
Italian
Speaking competence : Intermediate , Written competence : Intermediate -
Spanish
Speaking competence : Basic level , Written competence : Basic level
Computing skills
Software
Microsoft OfficeChemDraw
IsisDraw
MestreC
NMR Notebook
KyPlot
Beilstein
MDL Isis-Base
SciFinder
Adobe Acrobat
Various
Reading
Police novels
Historic novels
Cinema
Every kind of film
Music
Classic
Country
Rock
French & English varieties
Roller Blades
Amateur